MOTHER gives you an overview of all available help guides here. Plus a lot of background information.
Remember that MOTHER will always be here to help you.

• System Shock 2 Help Guides
• SS2 background info and statistics
• SS2 Editing
• System Shock resources
• System Shock background info and statistics
• Misc

System Shock 2 Help Guides

• Newbie Modding Guide
• Installation Guide (Technical FAQ)
• Trouble Shooting
• ZylonBane's Newbie Guide (spoilerfree gameplay tips)
• Multiplayer Guide
• Mod compatibility
• Headphones Sound Upgrade (advanced)

SS2 background info and statistics (incl. spoilers)

• System Shock Universe Timeline
• Fiction by Ken Levine bridging SS1 -> SS2
• Audiologs
• Audiolog Locations
• Weapons list
• Psi skill stats
• Chemical Manifest
• Cyber modules
• Objectives and Walkthroughs
• Manuals: English, Polish, German
• Prima's Official Strategy Guide
• Shevers' Deaths Guide
• Louise Brooks
• Missing log / Cut outs
• SS2 Soundtrack
• SS2 Music
• Level Blueprints

SS2 Editing

• ShockEd Basic Toolkit
• Shocked for Dummies
• Raph's ShockEd beginner video tutorials
• Basic ShockEd Tutorial (repeats shocked for dummies)
• Simple ShockEd FAQ
• Adv. ShockEd Tutorials
• Shocked Commands List
• Dave Angel's Texture Browser
• Shocked - Spanker's Motion List
• SS2 Modelling (video tutorial)
• SS2 AI mesh creation (video tutorial)
• SS2 unstripped missions
• How to make new biped Meshes for Dark Engine Games
• An Introduction to Scripts
• Ambient Sounds List
• SS2 General File Archive
• SS2 Mission Design Forum at TTLG
• TEG The Editors' Guild at TTLG

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System Shock resources

• SYSTEMSHOCK-Portable
• SHLINK (Running SS1 natively on Windows)
• Better music with BASS MIDI
• System Shock for Apple Macintosh
• Quick guide to run System Shock on Linux

System Shock background info and statistics (incl. spoilers)

• ICE Breaker (Handbook)
• LGS Manual & Reference card (English, German, French)
• System Shock audiologs English, German, French
• enemies stats
• weapons and ammo stats
• walkthrough & maps
• damage system
• grenades and explosives
• Looking Glass History

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Misc

• Welcome
• SS2Tool
• LGC Looking Glass Classics
• NewDark original releases: SS2 and Thief2

https://www.youtube.com/watch?v=RVAFyoTsqiQ